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Southampton host Liverpool in matchday 37 of Premier League 2021-22 at the St Mary’s Stadium on Wednesday, May 18. The match will kick off at 12:15 AM IST (Indian Standard Time).

Liverpool will assess Mohamed Salah and Virgil van Dijk for the trip to Southampton, given the line-up of fixtures in the pipeline. The pair limped off with minor injuries during the FA Cup final against Chelsea but as things stand, their injuries are not considered serious.

The Reds are already without Fabinho and might also rest right Andy Robertson who suffered a cramp in the Cup final win.

Southampton, on the other hand, have no fresh additions to the treatment table besides Valentino Livramento

Southampton vs Liverpool odds for Premier League 2021-22

Southampton: 7.60

Liverpool: 1.34

Draw: 5.80

Click here to check football betting odds.

Note: Odds are subject to change.

Southampton vs Liverpool recent form

Liverpool are coming on the back of a hard-fought FA Cup final against Chelsea, which kept their quadruple hopes alive. The Reds, currently second on the Premier League table, will need to win the tie so that they stay alive in the EPL title race.

Southampton, meanwhile, have won just two of their last 10 Premier League games. The Saints, 15th on the points table, lost 0-3 on the road at Brentford in their last outing.

Southampton: L, L, D, L, W

Liverpool: W, W, D, W, W

Southampton vs Liverpool head-to-head

Liverpool lead the head-to-head record against Southampton in the Premier League with 24 wins in 45 matches. Southampton have notched 11 victories in the process. 10 meetings have ended in a draw

The teams met earlier this season in November, where goals from Diogo Jota (two), Thiago Alcantara and Virgil van Dijk earned Jurgen Klopp’s men a 4-0 win at Anfield.

Liverpool have lost just one of their last Premier League matches against Southampton - the away tie in the 2020-21 season.

As far as the overall head-to-head is concerned, Liverpool have 59 wins in 115 games across all competitions. Southampton have claimed 31 victories, while the two sides have played out 25 stalemates.

Southampton vs Liverpool prediction and tips for Premier League 2021-22

Liverpool are backed by the odds to win this fixture. The Reds’ advantage in the head-to-head record against Southampton and the fact that they lost just one of their last 10 Premier League games against the Saints make them the favourites to win Wedneday’s clash against the Saints.

Featured photo: AFP / OLI SCARFF

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