Managers will be able to make up to five substitutions for the remainder of the 2019/20 Premier League season after clubs agreed to the temporary rule change at a meeting on Thursday.
FIFA proposed the solution last month to "protect player welfare" with a large number of matches packed into a few weeks to clear the backlog of a three-month layoff due to the global pandemic.
Premier League clubs also agreed to increase the number of substitutes available for selection from seven to nine for the remainder of the season.
"For the remainder of the 2019/20 season, the number of substitutes that can be used during a match will increase from three to five players," the Premier League said in a statement.
"This is in line with the temporary law amendment made by the International Football Association Board last month.
"Shareholders also approved for clubs to increase the maximum number of substitute players on the bench from seven to nine for the rest of the 2019/20 season."
To avoid too many stoppages, each team will still only have three opportunities to make changes as well as at half-time.
The Premier League will resume with two matches on June 17 as Manchester City host Arsenal and Sheffield United travel to Aston Villa.
The remaining nine full rounds of fixtures are then expected to be completed in just five weeks.
Feature image courtesy: AFP / Ian Kington